| Title | NWGAP | 
| Revision | 2.0 | 
| Purpose | Global sequence alignment | 
| Package type | Program | 
| Application area | Biomedical, Sequence alignment | 
| Abstract | NWGAP is a global sequence alignment program. NWGAP uses a modified version of the Needleman and Wunsch algorithm. The most signficant modification is that affine gap penalities can be used. Other modifications include user-defined reduced "set" alphabets. A variety of alignment methods can be selected, including match/mismatch, dayhoff pam-250, structure genetics, properties, and user-defined methods. NWGAP can be used to produce global alignments between two nucleic acid sequences, or two protein sequences. | 
| Submittor | Alex Ropelewski | 
| Contact | Alex Ropelewski | 
| Phone | 412-268-4960 | 
| ropelewski@psc.edu | |
| Company/ Institution  | Pittsburgh Supercomputing Center 4400 Fifth Avenue Pittsburgh, PA, 15213  | 
| CUG Site Code | PSC | 
| Distribution method | contact the following person: Alex Ropelewski | 
| URL | |
| Distribution restrictions | none | 
| Copyright | Copyright by PSC, with a free license to users to make a local copy. No redistribution is allowed. | 
| License required | no | 
| License fee | n.a. | 
| Hardware | |
| Operating System | UNICOS 6.0 | 
| Compiler(s) | CFT77 and C | 
| Program support | When schedule permits | 
| Documentation | README file, User Manual, test data | 
| Portability to other UNIX systems | Program is mixed FORTRAN and C. There will naturally be some porting problems. | 
| Additional comments | NWGAP uses the linear space version of the dynamic programming algorithm of Miller and Myers. |